2025 Lexus Es 350 Hybrid Mpg. Epa mpg owner mpg estimates 2025 lexus es 250 awd 4 cyl, 2.5 l, automatic (s8) regular gasoline The hybrid sedan earns epa fuel economy ratings of 44 mpg combined, 43 mpg city, 44 mpg highway;
Epa fuel economy, combined/city/highway (mpg). 1984 to present buyer’s guide to fuel efficient cars and trucks.